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KMID : 1101520200240010055
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Journal of Korean Society for Neurotherapy
2020 Volume.24 No. 1 p.55 ~ p.59
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Case report: Imaging of Corpus Callosum Agenesis
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Lee Kyoung-Bo
Lee Sang-Ho
Lim Seong-Hoon
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Abstract
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Purpose: Agenesis of the corpus callosum (AgCC) is one of several disorders of the structure that connects the two hemispheres of the brain. We describe two patients with AgCC and compare their magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) findings with those of healthy controls.
Methods: Two females with AgCC underwent brain MRI. DTI-Studio software (CMRM, Johns Hopkins Medical Institute, MD, USA) was used to reconstruct the corpus callosum (CC) fibers.
Results: MRI revealed periventricular plaques, complete CC agenesis of corpus callosum, and a residual anterior commissure (AC). In the DTI images of normal subjects, transcallosal fiber tracts were apparent, and formed many more connections to the frontal area than was the case in the patients.
Conclusion: Early diagnosis and intervention may improve the social and developmental outcomes of patients with AgCC. Symptoms and seizures must be managed. A focus on right/left co-ordination render the condition much more manageable than is otherwise the case.
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KEYWORD
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Agenesis of the corpus callosum, Clinical findings, MRI, Diffusion tensor imaging
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